Magnetic molecularly imprinted polymers (MIPs) for urea were prepared using konjac glucomannan (KGM) as the substrate, methacrylic acid as the graft comonomer, ethylene glycol dimethacrylate as the cross-linker, urea as the template molecule, and Fe₃O₄ NPs as the magnetic ingredient. The resultant MIPs were characterized by Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, X-ray diffraction, transmission electron microscopy, thermogravimetric analysis, vibrating sample magnetometry, and Brunauer–Emmett–Teller spectroscopy. The MIPs possessed high superparamagnetism with core–shell structures, which could be easily separated from the mixture by an external magnetic field. The MIPs could specifically recognize urea, and the recognition capacity and adsorption performance remained almost unchanged after three cycles of adsorption and elution. The adsorption kinetics of MIPs on urea could be described by the second-order kinetic model. The maximum adsorption capacity of MIPs on urea was 16.80 mg/g, and the adsorption isotherms of MIPs on urea followed the Langmuir model. In addition, in vitro adsorption experiments through simulated body fluids showed that the MIPs had good adsorption capacity for urea. The product is expected to be used as a novel adsorption material for blood purification.

以魔芋葡甘露聚糖（KGM）为底物，甲基丙烯酸为接枝共聚单体，乙二醇二甲基丙烯酸酯为交联剂，尿素为模板分子和Fe ₃ O ₄制备了尿素的磁性分子印迹聚合物（MIP）。NPs作为磁性成分。通过傅立叶变换红外光谱，X射线光电子能谱，X射线衍射，透射电子显微镜，热重分析，振动样品磁强和Brunauer-Emmett-Teller光谱对所得的MIP进行了表征。MIP具有高超顺磁性和核-壳结构，可以很容易地通过外部磁场将其与混合物分离。MIP可以特异性识别尿素，经过三个吸附和洗脱循环后，识别能力和吸附性能几乎保持不变。MIPs在尿素上的吸附动力学可以通过二级动力学模型来描述。MIPs在尿素上的最大吸附容量为16.80 mg / g，MIPs在尿素上的吸附等温线遵循朗缪尔模型。此外，通过模拟体液进行的体外吸附实验表明，MIP具有良好的尿素吸附能力。该产品有望用作血液净化的新型吸附材料。