In this study, a pH-sensing electrospun mat containing purple cabbage (PC) (Brassica oleracea) anthocyanins was developed for wound dressing application. The pH-sensing electrospun mat was prepared from sodium alginate (Alg) and poly (vinyl alcohol) (PVA) via electrospinning. PC anthocyanins were embedded into the electrospun mat with the addition of PC extract into the Alg/PVA electrospun solution. The characterization studies were conducted by scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), water contact angle (WCA) and thickness measurements. The halochromic behavior of the pH-sensing Alg/PVA/PC electrospun mat was elucidated via UV–Vis spectrophotometric analyses and color measurements obtained from quantitative color data. In vivo performance of the pH-sensing mat was evaluated by animal studies. The electrospun mat was successfully used to monitor pH changes of an open wound. In addition, wound healing efficacy of the electrospun mat was compared with a commercial wound dressing. The results revealed that a wound dressing benefiting from halochromic properties of the anthocyanins besides wound healing efficacy of Alg was successfully developed. The pH-sensing Alg/PVA/PC electrospun mat has a usage potential for wound dressing applications especially for monitoring wound status on real-time during healing period.

在这项研究中，pH感应电纺垫包含紫甘蓝（Brassica oleracea）开发出花青素用于伤口敷料。通过海藻酸钠（Alg）和聚乙烯醇（PVA）通过静电纺丝制备pH值感应电纺垫。将PC花青素嵌入电纺垫中，然后将PC提取物添加到Alg / PVA电纺溶液中。通过扫描电子显微镜（SEM），傅立叶变换红外光谱（FTIR），水接触角（WCA）和厚度测量进行表征研究。通过UV-Vis分光光度法分析和从定量颜色数据获得的颜色测量结果阐明了pH敏感的Alg / PVA / PC电纺垫的变色行为。通过动物研究评估了pH传感垫的体内性能。电纺垫成功地用于监测开放伤口的pH变化。此外，将电纺垫的伤口愈合功效与商业伤口敷料进行了比较。结果表明，除Alg的伤口愈合功效外，还开发了受益于花色苷的盐致变色性质的伤口敷料。pH敏感型Alg / PVA / PC电纺垫具有用于伤口敷料的潜在用途，尤其是在愈合期间实时监测伤口状态时。