Autism spectrum disorder (ASD) is comprised of several conditions characterized by alterations in social interaction, communication, and repetitive behaviors. Genetic and environmental factors contribute to the heterogeneous development of ASD behaviors. Several rodent models display ASD-like phenotypes, including repetitive behaviors. In this review article, we discuss the potential neural mechanisms involved in repetitive behaviors in rodent models of ASD and related neuropsychiatric disorders. We review signaling pathways, neural circuits, and anatomical alterations in rodent models that display robust stereotypic behaviors. Understanding the mechanisms and circuit alterations underlying repetitive behaviors in rodent models of ASD will inform translational research and provide useful insight into therapeutic strategies for the treatment of repetitive behaviors in ASD and other neuropsychiatric disorders.

自闭症谱系障碍 (ASD) 由多种以社交互动、沟通和重复行为改变为特征的病症组成。遗传和环境因素导致自闭症谱系障碍行为的异质性发展。一些啮齿动物模型表现出类似自闭症谱系障碍的表型，包括重复行为。在这篇综述文章中，我们讨论了自闭症谱系障碍和相关神经精神疾病啮齿动物模型中重复行为所涉及的潜在神经机制。我们回顾了啮齿动物模型中表现出稳健刻板行为的信号通路、神经回路和解剖学改变。了解 ASD 啮齿动物模型中重复行为的机制和回路改变将为转化研究提供信息，并为治疗 ASD 和其他神经精神疾病的重复行为的治疗策略提供有用的见解。