The alarming growth of antimicrobial resistance and recent viral pandemic events have enhanced the need for novel approaches through innovative agents that are mainly able to attach to the external layers of bacteria and viruses, causing permanent damage. Antimicrobial molecules are potent broad-spectrum agents with a high potential as novel therapeutics. In this context, antimicrobial peptides, cell penetrating peptides, and antiviral peptides play a major role, and have been suggested as promising solutions. Furthermore, dendrimers are to be considered as suitable macromolecules for the development of advanced nanosystems that are able to complement the typical properties of dendrimers with those of peptides. This review focuses on the description of nanoplatforms constructed with peptides and dendrimers, and their applications.

中文翻译：

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肽和树状聚合物：如何抵抗病毒和细菌感染

令人惊讶的是，抗菌素耐药性的增长和最近发生的病毒大流行事件，使得人们需要通过创新的药物来开发新颖的方法，这些药物主要能够附着在细菌和病毒的外层，从而造成永久性破坏。抗菌分子是有效的广谱药物，具有作为新疗法的高潜力。在这种情况下，抗菌肽，细胞穿透肽和抗病毒肽起着重要作用，并被认为是有前途的解决方案。此外，树状聚合物被认为是用于开发先进的纳米系统的合适的大分子，该先进的纳米系统能够用肽的性质来补充树状聚合物的典型性质。这篇综述着重于用肽和树状大分子构建的纳米平台的描述及其应用。