Visible‐Light‐Promoted Switchable Synthesis of C‐3‐Functionalized Quinoxalin‐2(1H)‐ones,Advanced Synthesis & Catalysis

当前位置： X-MOL 学术 › Adv. Synth. Catal. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Visible‐Light‐Promoted Switchable Synthesis of C‐3‐Functionalized Quinoxalin‐2(1H)‐ones
Advanced Synthesis & Catalysis ( IF 4.4 ) Pub Date : 2021-01-13 , DOI: 10.1002/adsc.202001396
Kim Christopher C. Aganda _{1,

2} , Boseok Hong ₃ , Anna Lee ₂

Affiliation

A visible‐light‐promoted synthesis of quinoxalin‐2(1H)‐ones has been developed using 9‐mesityl‐10‐methylacridinium perchlorate as an organo‐photocatalyst. The atmosphere‐controlled method (Ar/air) enabled the selective synthesis of hydroxyl‐ and acyl‐containing quinoxalin‐2(1H)‐ones under mild reaction conditions without the use of any metal catalysts or toxic reagents. A fluorescent labelling experiment showed that hydroxyl‐containing quinoxalin‐2(1H)‐ones may have utility in various biological applications as potent fluorophores.

中文翻译：

可见光促进的C-3功能化喹喔啉-2（1H）-one的可切换合成。

可见光促进了喹喔啉-2（1 H）-one的合成，该合成使用9-间苯甲基-1-10-甲基ac啶高氯酸盐作为有机光催化剂。气氛控制方法（Ar / air）使得在温和的反应条件下无需使用任何金属催化剂或有毒试剂即可选择性合成含羟基和酰基的喹喔啉-2（1 H）-酮。荧光标记实验表明，含羟基的喹喔啉-2（1 H）-酮类可以作为有效的荧光团在各种生物学应用中发挥作用。

更新日期：2021-03-03

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11