Journal of Photochemistry and Photobiology A: Chemistry ( IF 4.1 ) Pub Date : 2021-01-14 , DOI: 10.1016/j.jphotochem.2021.113145 Swathy S , Sanu K. Anand , Manna Rachel Mathew , K. Girish Kumar
A simple and highly selective turn-on fluorescence sensor has been developed for 5-hydroxyindoleacetic acid (5-HIAA) using thioglycolic acid capped cadmium sulphide quantum dots (TGA-CdS QDs). 5-HIAA enhances the fluorescence intensity of CdS QDs via aggregation-induced emission enhancement mechanism [AIEE]. Different sensor conditions have been optimized and under such conditions, the sensor achieved the quantification of 5-HIAA in the range of 2.5 × 10−6 M to 8.0 × 10-5 M with a limit of detection (LOD) of 8.4 × 10-7 M. The reliability of the sensor towards 5-HIAA detection has been proved by its successful application in synthetic urine and blood serum.
中文翻译:
巯基乙酸封端的硫化镉量子点,用作开启荧光传感器,用于测定5-羟基吲哚乙酸
使用巯基乙酸封端的硫化镉量子点(TGA-CdS QD),开发了一种用于5-羟基吲哚乙酸(5-HIAA)的简单且高度选择性的开启荧光传感器。5-HIAA通过聚集诱导的发射增强机制[AIEE]增强CdS QD的荧光强度。不同的传感器的条件进行了优化,并在这样的条件下,该传感器在2.5×10的范围内实现的5-HIAA的定量-6 M至8.0×10 -5米,8.4×10检测(LOD)的限制- 7 M.该传感器在合成尿液和血清中的成功应用证明了其对5-HIAA检测的可靠性。