Movies depicting certain types of motion often provoke uncomfortable symptoms similar to motion sickness, termed visually induced motion sickness (VIMS). VIMS generally evolves slowly during the viewing of a motion stimulus and, when the stimulus is removed, the recovery proceeds over time. Recent human neuroimaging studies have provided new insights into the neural bases of the evolution of VIMS. In contrast, no study has investigated the neural correlates of the recovery from VIMS. Study of the recovery process is critical for the development of a way to promote recovery and could provide further clues for understanding the mechanisms of VIMS. We thus investigated brain activity during the recovery from VIMS with functional connectivity magnetic resonance imaging. We found enhanced recovery-related functional connectivity patterns involving brain areas such as the insular, cingulate and visual cortical regions, which have been suggested to play important roles in the emergence of VIMS. These regions also constituted large interactive networks. Furthermore, the increase in functional connectivity was correlated with the subjective awareness of recovery for the following five pairs of brain regions: insula–superior temporal gyrus, claustrum–left and right inferior parietal lobules, claustrum–superior temporal gyrus and superior frontal gyrus–lentiform nucleus. Considering the previous findings on the functions of these regions and the present results, it is suggested that the increase in FC may reflect brain processes such as enhanced interoceptive awareness to one’s own bodily state, a neuroplastic change in visual-processing circuits and/or the maintenance of visual spatial memory.

描绘某些类型的运动的电影通常会引起类似于晕车的不适症状，称为视觉诱发晕车（VIMS）。VIMS通常在查看运动刺激时会缓慢发展，并且当移除刺激时，恢复会随着时间的推移而进行。最近的人类神经影像学研究为VIMS进化的神经基础提供了新的见解。相反，没有研究调查过从VIMS中恢复的神经相关性。对恢复过程的研究对于开发促进恢复的方法至关重要，并且可以为了解VIMS的机制提供进一步的线索。因此，我们使用功能连接磁共振成像技术从VIMS恢复期间调查了大脑活动。我们发现增强的与恢复相关的功能连接模式涉及大脑区域，如岛状，扣带状和视觉皮层区域，这些被建议在VIMS的出现中发挥重要作用。这些地区还构成了大型的互动网络。此外，功能连接性的增加与以下五对大脑区域的恢复主观认识有关：岛上-颞颞回，锁骨-左右左右顶叶，锁骨-颞颞回和额叶上回-扁形核。考虑到先前有关这些区域功能的发现和目前的结果，建议FC的增加可能反映了大脑过程，例如对自身身体状态的感知觉知觉增强，