Background Antipsychotic agents are associated with harmful adverse reactions which impact negatively on patient adherence and clinical management. Accurate and complete documentation of signs and symptoms in the clinical notes is an important means of communication between healthcare providers, and an essential component in the management of antipsychotic-induced adverse drug reactions. Aim To determine the impact of an educational intervention on the incidence and extent of antipsychotic-induced adverse drug reaction documentation in patient medical records. Setting The research was conducted in an acute care, public sector psychiatric facility in the Eastern Cape province of South Africa. Methods A quasi-experimental, before and after method was used, which focused on an educational intervention. The study design consisted of three phases: pre-intervention, intervention and post-intervention. A clinical audit was conducted, reviewing 102 patient medical records in the pre-intervention phase and a further 102 patient medical records in the post-intervention phase, in order to determine the impact of the intervention on the frequency and extent of documentation of suspected antipsychotic-induced adverse drug reactions Results Following the educational intervention, documentation of adverse drug reactions to antipsychotic drugs increased from 66 instances in the pre-intervention phase to 82 instances in the post-intervention phase. A statistically significant increase (Pearson’s Chi-square p < 0.05) was observed in the number of patient medical records that identified suspected adverse drug reactions. Conclusion The educational intervention was found to increase the incidence of documentation of adverse drug reactions, and increased awareness of the potential adverse drug reactions associated with antipsychotic drugs following the intervention.

中文翻译：

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抗精神病药物相关药物不良反应的记录：教育干预

背景 抗精神病药物与有害的不良反应有关，对患者的依从性和临床管理产生负面影响。在临床记录中准确和完整地记录体征和症状是医疗保健提供者之间沟通的重要手段，也是管理抗精神病药物引起的药物不良反应的重要组成部分。目的 确定教育干预对患者病历中抗精神病药物引起的药物不良反应记录的发生率和程度的影响。设置 该研究是在南非东开普省的一家急症护理公共部门精神病院进行的。方法 采用准实验前后的方法，侧重于教育干预。研究设计包括三个阶段：干预前、干预和干预后。进行了临床审计，审查了干预前阶段的 102 份患者病历和干预后阶段的另外 102 份患者病历，以确定干预对疑似抗精神病药物记录的频率和范围的影响- 诱发的药物不良反应 结果 在教育干预之后，记录对抗精神病药物的不良药物反应从干预前阶段的 66 例增加到干预后阶段的 82 例。在确定可疑药物不良反应的患者医疗记录数量中观察到统计学显着增加（Pearson 卡方 p < 0.05）。