OBJECTIVE The purpose of this study was to evaluate the costs and cost-effectiveness of two treatments for 101 alcohol use disorder patients and their intimate partners--group behavioral couples' therapy plus individual-based treatment (G-BCT), or standard behavioral couples' therapy plus individual-based treatment (S-BCT). METHOD We estimated the per-patient cost of each intervention using a microcosting approach that allowed us to estimate costs of specific components in each intervention as well as the overall total costs. Using simple means analysis and multiple regression models, we estimated the incremental effectiveness of G-BCT relative to S-BCT. Immediately after treatment and 12 months after treatment, we computed incremental cost-effectiveness ratios (ICER) and cost-effectiveness acceptability curves for percentage days abstinent, adverse consequences of alcohol and drugs, and overall relationship functioning. RESULTS The average per-patient cost of delivering G-BCT was $674, significantly less than the cost of S-BCT ($831). However, 12 months after treatment, S-BCT participants performed better on all outcomes compared with those in G-BCT, and the calculated ICER moving from G-BCT to S-BCT ranged from $10 to $12 across these outcomes. The current findings indicated that, except at very low willingness-to-pay values, S-BCT is a cost-effective option relative to G-BCT when considering 12-month posttreatment outcomes. CONCLUSIONS As expected, G-BCT was delivered at a lower cost per patient than S-BCT; however, S-BCT performed better over time on the clinical outcomes studied. These economic findings indicate that alcohol use disorder treatment providers should seriously consider S-BCT over G-BCT when deciding what format to use in behavioral couples' therapy.

中文翻译：

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小组与标准行为伴侣对酒精使用障碍患者的治疗：成本-效果

目的本研究的目的是评估针对101名酒精使用障碍患者及其亲密伴侣的两种疗法的成本和成本效益-团体行为伴侣疗法加上个人治疗（G-BCT）或标准行为伴侣疗法加基于个体的疗法（S-BCT）。方法我们使用微成本法估算了每种干预措施的每位患者成本，该方法使我们能够估算每种干预措施中特定组成部分的成本以及总的总成本。使用简单的均值分析和多元回归模型，我们估计了G-BCT相对于S-BCT的增量有效性。治疗后立即和治疗后12个月，我们计算了禁忌日数，酒精和药物的不良后果以及整体关系运行的增量成本效益比（ICER）和成本效益可接受性曲线。结果提供G-BCT的平均每位患者费用为674美元，大大低于S-BCT的费用（831美元）。但是，治疗后12个月，S-BCT参与者的所有结局均优于G-BCT，在这些结局中，从G-BCT到S-BCT的计算ICER从10美元到12美元不等。当前的研究结果表明，除了支付意愿非常低外，考虑到12个月的治疗后结局，相对于G-BCT，S-BCT是一种经济高效的选择。结论正如预期的那样，G-BCT的每位患者费用比S-BCT低。然而，随着时间的推移，S-BCT在所研究的临床结果中表现更好。这些经济发现表明，酒精滥用障碍治疗提供者在决定以行为伴侣的治疗方式使用时应认真考虑S-BCT而非G-BCT。