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Health-Related Quality of Life, Functioning and Social Experiences in People with Psychotic Disorders
Applied Research in Quality of Life ( IF 2.8 ) Pub Date : 2020-05-29 , DOI: 10.1007/s11482-020-09845-y
Adriana G. Nevarez-Flores , Vera A. Morgan , Carol Harvey , Monique Breslin , Vaughan J. Carr , Kristy Sanderson , Anna Waterreus , Amanda L. Neil

To inform development of a model for health-related quality of life (HRQoL) in people with psychotic disorders, we aimed to assess correlations between utilities and dimension scores for the Assessment of Quality of Life (AQoL)-4D with functioning and social experiences; ascertain if patient housing and clinical status affected correlations; and determine aspects of functioning that jointly predict HRQoL. We analyzed data for 1642 people with an ICD-10 psychotic disorder from the 2010 Australian National Survey of Psychosis. Global functioning was measured with the Personal and Social Performance scale, independent functioning with the Multidimensional Scale of Independent Functioning and social functioning through level of social dysfunction. Social experiences comprised perceived loneliness and experienced stigma. We assessed Spearman’s rank correlation coefficients and undertook linear regression analyses. Moderate associations were found between AQoL-4D utilities and all variables, except experienced stigma. Perceived loneliness had the strongest association. The AQoL-4D social relationships dimension was most strongly associated with social variables; its independent living dimension with global and independent functioning. Correlations between utilities and all variables, except for social dysfunction, were modified by housing. Course of disorder impacted correlations with utilities and independent functioning. Global functioning and social dysfunction were found to jointly predict HRQoL. In conclusion, as the AQoL-4D can differentiate between functioning and social experiences individually and when categorized by housing and clinical status in people with psychosis, predictive models of HRQoL in this population are feasible, and only need include select aspects of functioning and social experiences, particularly perception of loneliness.



中文翻译:

精神病患者的健康相关生活质量、功能和社交体验

为了为精神病患者的健康相关生活质量 (HRQoL) 模型的开发提供信息,我们旨在评估效用和生活质量评估 (AQoL)-4D 维度评分与功能和社会经验之间的相关性;确定患者住房和临床状态是否影响相关性;并确定共同预测 HRQoL 的功能方面。我们分析了 2010 年澳大利亚全国精神病调查中 1642 名 ICD-10 精神病患者的数据。全球功能是用个人和社会绩效量表来衡量的,独立功能是用独立功能的多维量表和社会功能通过社会功能障碍的水平来衡量的。社会经历包括感知到的孤独感和经历过的耻辱感。我们评估了斯皮尔曼等级相关系数并进行了线性回归分析。在 AQoL-4D 实用程序和所有变量之间发现了中等关联,除了经历过的耻辱。感知孤独具有最强的关联。AQoL-4D 社会关系维度与社会变量的相关性最强;其独立的生活维度,具有全球和独立的功能。公用事业和所有变量之间的相关性,除了社会功能障碍,都被住房改变了。无序过程会影响与效用和独立功能的相关性。发现全球功能和社会功能障碍共同预测 HRQoL。综上所述,

更新日期:2020-05-29
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