The study aimed to analyze the scientific production on the association between asthma and type 2 diabetes mellitus (T2DM) in adults, the mechanisms that explain this association, and its impact on asthma control. A literature review of scientific articles indexed in the MEDLINE/PUBMED, BVS, CINAHL, Cochrane Library, and Web of Science databases was carried out, considering publications from January 2009 to December 2019, using the following descriptors: “asthma”, “type 2 diabetes”, “adult,” and “association”. Of 962 articles found, 18 were included because they met the eligibility criteria. It is suggested that the association between asthma and T2DM is caused by low-grade systemic inflammation (7 articles) or the use of corticosteroids (7 articles). It is noticed that there is a limited scientific production regarding the consequences of this association for the control of asthma (5 articles). It is concluded that asthma and T2DM are two common chronic conditions of increasing prevalence and that often coexist in the same patient. It is suggested that this coexistence worsens asthma control. Therefore, the study may support public policies and clinical health practices that value the approach of comorbidities associated with asthma such as T2DM, in order to minimize additional health risks and reduce the quality of life.

中文翻译：

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哮喘与 2 型糖尿病之间的关联：机制及其对哮喘控制的影响——文献综述


该研究旨在分析成人哮喘与 2 型糖尿病 (T2DM) 之间关联的科学成果、解释这种关联的机制及其对哮喘控制的影响。对 MEDLINE/PUBMED、BVS、CINAHL、Cochrane 图书馆和 Web of Science 数据库中索引的科学文章进行了文献综述，考虑了 2009 年 1 月至 2019 年 12 月的出版物，使用以下描述符：“哮喘”、“2 型”糖尿病”、“成人”和“关联”。在找到的 962 篇文章中，有 18 篇因符合资格标准而被纳入。有人认为哮喘与 T2DM 之间的关联是由低度全身炎症（7 篇文章）或皮质类固醇的使用（7 篇文章）引起的。值得注意的是，关于这种关联对哮喘控制的影响的科学成果有限（5 篇文章）。结论是，哮喘和 T2DM 是两种常见的慢性病，​​患病率不断增加，并且经常在同一患者身上同时存在。有人认为这种共存会使哮喘控制恶化。因此，该研究可能支持重视治疗 T2DM 等哮喘相关合并症的公共政策和临床健康实践，以尽量减少额外的健康风险并降低生活质量。