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Antimicrobial Resistance in Escherichia coli Strains Isolated from Humans and Pet Animals
Antibiotics ( IF 4.3 ) Pub Date : 2021-01-13 , DOI: 10.3390/antibiotics10010069
Nikola Puvača 1, 2 , Rosa de Llanos Frutos 1
Affiliation  

Throughout scientific literature, we can find evidence that antimicrobial resistance has become a big problem in the recent years on a global scale. Public healthcare systems all over the world are faced with a great challenge in this respect. Obviously, there are many bacteria that can cause infections in humans and animals alike, but somehow it seems that the greatest threat nowadays comes from the Enterobacteriaceae members, especially Escherichia coli. Namely, we are witnesses to the fact that the systems that these bacteria developed to fight off antibiotics are the strongest and most diverse in Enterobacteriaceae. Our great advantage is in understanding the systems that bacteria developed to fight off antibiotics, so these can help us understand the connection between these microorganisms and the occurrence of antibiotic-resistance both in humans and their pets. Furthermore, unfavorable conditions related to the ease of E. coli transmission via the fecal–oral route among humans, environmental sources, and animals only add to the problem. For all the above stated reasons, it is evident that the epidemiology of E. coli strains and resistance mechanisms they have developed over time are extremely significant topics and all scientific findings in this area will be of vital importance in the fight against infections caused by these bacteria.

中文翻译:


从人类和宠物中分离出的大肠杆菌菌株的抗菌药物耐药性



在整个科学文献中,我们可以找到证据表明抗菌素耐药性近年来已成为全球范围内的一个大问题。世界各地的公共卫生体系在这方面都面临着巨大的挑战。显然,有许多细菌可以引起人类和动物感染,但不知何故,当今最大的威胁似乎来自肠杆菌科成员,尤其是大肠杆菌。也就是说,我们见证了这样一个事实:这些细菌为抵抗抗生素而开发的系统是肠杆菌科中最强大和最多样化的。我们的巨大优势在于了解细菌抵抗抗生素的系统,因此这些可以帮助我们了解这些微生物与人类及其宠物的抗生素耐药性发生之间的联系。此外,大肠杆菌通过粪口途径在人类、环境来源和动物之间传播的便利性相关的不利条件只会加剧问题。出于所有上述原因,很明显,大肠杆菌菌株的流行病学及其随着时间的推移而形成的耐药机制是极其重要的话题,该领域的所有科学发现对于对抗由这些菌株引起的感染至关重要。细菌。
更新日期:2021-01-13
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