We previously showed that the hybridization of water-insoluble 12-hydroxystearic acid (HSA) with water-soluble long-chain amidoamine derivatives yields hydrogels composed of self-assembled helical nanofibers. In this work, we investigated the effect of introducing an amide group into the alkyl chain of amidoamine derivatives on the helical structure of the nanofibers. We also demonstrated that improving the solubility of HSA by changing the gelation solvent is a very effective method of preparing homogeneous nanofibers composed of two compounds.

中文翻译：

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通过调节胶凝溶剂制备的12-羟基硬脂酸和长链酰胺胺衍生物的均相螺旋纳米纤维

我们以前表明水不溶性12-羟基硬脂酸（HSA）与水溶性长链酰胺基胺衍生物的杂交产生了由自组装螺旋纳米纤维组成的水凝胶。在这项工作中，我们研究了将酰胺基引入酰胺基胺衍生物的烷基链上对纳米纤维螺旋结构的影响。我们还证明了通过改变凝胶溶剂来提高HSA的溶解度是制备由两种化合物组成的均相纳米纤维的一种非常有效的方法。