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Recent advances in microencapsulation of drugs for veterinary applications
Journal of Veterinary Pharmacology and Therapeutics ( IF 1.5 ) Pub Date : 2021-01-13 , DOI: 10.1111/jvp.12946
Salah Uddin Ahmad 1, 2, 3, 4 , Bing Li 1, 2, 3 , Jichao Sun 1, 2, 3 , Safia Arbab 1, 2, 3 , Zhen Dong 1, 2, 3 , Fusheng Cheng 1, 2, 3 , Xuzheng Zhou 1, 2, 3 , Shad Mahfuz 4 , Jiyu Zhang 1, 2, 3
Affiliation  

Microencapsulation is a process where very minute droplets or particles of solid or liquid or gas are trapped with a polymer to isolate the internal core material from external environmental hazards. Microencapsulation is applied mostly for flavor masking, fortification, and sustained and control release. It improves palatability, absorption, and bioavailability of drugs with good conformity. Microencapsulation has been widely studied in numerous drug delivery systems for human health. The application of microcapsules in the veterinary pharmaceutical sciences is increasing day by day. The treatment systems for humans and animals are likely to be similar, but more complex in the veterinary field due to the diversity of the species, breeds, body size, biotransformation rate, and other factors associated with animal physiology. Commercially viable, economically profitable, and therapeutically effective microencapsulated vaccine, anthelmintic, antibacterial, and other therapeutics have a great demand for livestock and poultry production. Nowadays, researchers emphasize the controlled and sustained-release dosage form of drugs in the veterinary field. This paper has highlighted the microencapsulation materials, preparation techniques, characteristics, roles, and the application of microcapsules in veterinary medicine.

中文翻译:

兽医应用药物微胶囊化的最新进展

微囊化是一种过程,其中非常微小的固体或液体或气体的液滴或颗粒被聚合物捕获,以将内部核心材料与外部环境危害隔离开来。微胶囊主要用于掩味、强化以及持续和控制释放。它提高了药物的适口性、吸收性和生物利用度,具有良好的一致性。微囊化已在许多用于人类健康的药物递送系统中得到广泛研究。微胶囊在兽药科学中的应用日益增多。由于物种、品种、体型、生物转化率和其他与动物生理相关的因素的多样性,人类和动物的治疗系统可能相似,但在兽医领域更为复杂。商业上可行,经济上有利可图、疗效显着的微囊疫苗、驱虫药、抗菌药等治疗剂对畜禽生产有很大的需求。如今,研究人员在兽医领域强调药物的控释和缓释剂型。本文重点介绍了微胶囊的材料、制备技术、特点、作用以及微胶囊在兽药中的应用。
更新日期:2021-01-13
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