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Multi-walled carbon nanotubes decorated with silver nanoparticles for antimicrobial applications
Journal of Environmental Chemical Engineering ( IF 7.4 ) Pub Date : 2021-01-13 , DOI: 10.1016/j.jece.2021.105034
H.I. Hamouda , H.M. Abdel-Ghafar , M.H.H. Mahmoud

Great attention has been paid to antimicrobial agents' development to face and control infection transmission of infectious diseases spreading. Decorated multi-walled carbon nanotubes (MWCNTs) with silver nanoparticles (Ag NPs) are useful substances with antibacterial potency that might be used for a wide range of medical applications and water disinfection to limit the spreading of infectious diseases. In this work, silver nanoparticles were loaded on the surface of MWCNTs via the wet-impregnation technique followed by thermal treatment at 450 °C for 4 h in an inert atmosphere. Different ratios of Ag NPs (0, 3, 6, 12 and 24) were loaded on the surface of MWCNTs. The synthesized Ag-MWCNTs nanocomposites were characterized by XRD, XPS, and TEM. The antibacterial efficacy of Ag-MWCNTs nanocomposites was tested towards different microbial strains (bacteria and fungus); P. aeruginosa, E. coli, B. subtilis, S. aureus, C. albicans, and A. niger, which proved the wide spectrum of Ag-MWCNTs. The synthesized nanocomposite showed a higher antimicrobial capability against gram-positive than gram-negative bacteria. Biological studies indicated a large inhibition zone for each bacterial strain that reaches 18.5 mm. SEM and fluorescent microscopy were tested to examine the structural disruption in the outer membranes after incubation with the antibacterial agent. The nanocomposite firmly agglutinated to the surface of the bacterial cells, leading to cells' wrapping, morphology deterioration, and cell death. The inhibition ability of Ag-MWCNTs nanocomposite with a broad spectrum of microorganisms provides exciting opportunities to enhance and maximize potable water disinfection and medical applications to control infectious diseases spreading.



中文翻译:

用纳米银装饰的多壁碳纳米管用于抗菌应用

人们已经非常重视抗菌剂的开发,以面对和控制传染病传播的传播途径。带有银纳米颗粒(Ag NPs)的装饰多壁碳纳米管(MWCNT)是有用的具有抗菌效力的物质,可广泛用于医疗应用和水消毒,以限制传染病的传播。在这项工作中,通过湿法浸渍技术将银纳米颗粒装载到MWCNT的表面,然后在惰性气氛中于450°C热处理4 h。将不同比例的Ag NP(0、3、6、12和24)装载到MWCNT的表面上。利用XRD,XPS和TEM对合成的Ag-MWCNTs纳米复合材料进行了表征。铜绿假单胞菌大肠杆菌枯草芽孢杆菌金黄色葡萄球菌白色念珠菌黑曲霉这证明了Ag-MWCNT的广谱性。合成的纳米复合材料显示出比革兰氏阴性细菌更高的抗革兰氏阳性细菌的能力。生物学研究表明,每种细菌菌株都有一个较大的抑制区,达到18.5 mm。与抗菌剂一起孵育后,通过SEM和荧光显微镜检查了外膜的结构破坏。纳米复合材料牢固地凝集在细菌细胞的表面,导致细胞包裹,形态恶化和细胞死亡。具有多种微生物的Ag-MWCNTs纳米复合材料的抑制能力为增强和最大化饮用水消毒和医疗应用以控制传染病的传播提供了令人兴奋的机会。

更新日期:2021-01-22
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