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Inhibition of Phosphotidylcholine Liposome Oxidation by Phenolics from Aloe Extracts: A. arborescens , A. pillansii , and A. squarrosa
Russian Journal of Bioorganic Chemistry ( IF 1.1 ) Pub Date : 2021-01-13 , DOI: 10.1134/s1068162020070146
N. N. Sazhina , P. V. Lapshin , N. V. Zagoskina , N. P. Palmina

Abstract

Various species from the genus Aloe, which there are more than 500 in the world, are considered to be important sources of biologically active compounds, and their numerous biological qualities are attracting research interest. Of Aloe species, A. arborescens and A. vera are the most studied and used; however, some other species from this genus exhibit no less biological activity, in particular, antioxidant activity, than these two. In this work, the antioxidant activity of extracts obtained from A. аrborescens, A. pillansii, and A. squarrosa leaves is evaluated and compared using the model of initiated oxidation of phosphotidylcholine liposomes, and their total phenolic content is determined. The antioxidant activity of A. pillansii extract was ~12 and 4 times greater than that of A. arborescens and A. squarrosa, respectively. However, the difference in the total phenolic content of these extracts is not so large, suggesting that A. pillansii leaves may have a more complex antioxidant profile and a higher concentration of active phenolic metabolites than does A. arborescens. The findings of this study inspire further research into the biological activity of A. pillansii.



中文翻译:

芦荟提取物中的酚类物质对磷脂酰胆碱脂质体的抑制作用:A。arborescens,A。pillansii和A. squarrosa

摘要

世界上有500多个芦荟属物种被认为是生物活性化合物的重要来源,其众多的生物学特性引起了人们的研究兴趣。在芦荟种类中,研究最多的是使用了A. arborescensA. vera。然而,来自该属的其他一些物种表现出的生物学活性,特别是抗氧化活性,不低于这两个物种。在这项工作中,从A.áborescensA。pillansiiA. squarrosa获得的提取物的抗氧化活性使用磷脂酰胆碱脂质体的起始氧化模型评估和比较叶片,并确定其总酚含量。的抗氧化活性A. pillansii提取物比的更大〜12倍和4倍A.藜A.草,分别。然而,在这些提取物的总酚含量的差不那么大,这表明A. pillansii叶可以具有更复杂的抗氧化剂分布和比确实活性代谢物的酚的浓度越高A.藜。这项研究的结果激发了对毛兰线虫生物学活性的进一步研究。

更新日期:2021-01-13
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