Benzimidazole is the heterocyclic compound formed by the fusion of benzene and imidazole ring. Benzimidazole analogs are of great significance because of their clinical application and biological activity. Benzimidazoles are considered as an optimistic class of bioactive heterocyclic compound that possesses a range of biological activities. We have synthesized five substituted Benzimidazole derivative using on both microwave irradiation and conventional heating method. The newly synthesized compounds are characterized by IR, NMR and Mass spectra analysis. In the present study, we have reported the synthesis, spectral studies and biological evaluation of some benzimidazole derivatives. Benzimidazole play important role in medical field with so many pharmacological activities such as antimicrobial, anti bacterial, etc. The potency of this clinically useful drug in treatment in microbial action and other activities has encouraged the development of some more potent and significant compounds.

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2-取代的苯并咪唑衍生物的合成，表征及有效的抗菌和抗真菌活性

苯并咪唑是由苯和咪唑环稠合形成的杂环化合物。苯并咪唑类似物由于其临床应用和生物学活性而具有重要意义。苯并咪唑被认为是具有一系列生物活性的一类乐观的生物活性杂环化合物。我们通过微波辐射和常规加热方法合成了五种取代的苯并咪唑衍生物。通过IR，NMR和质谱分析对新合成的化合物进行表征。在本研究中，我们已经报道了一些苯并咪唑衍生物的合成，光谱研究和生物学评估。苯并咪唑在医学领域起着重要的作用，它具有多种药理活性，例如抗微生物，抗细菌等。