M6A methyltransferases, acting as a writer in N6-methyladenosine, have attracted wide attention due to their dynamic regulation of life processes. In this review, we first briefly introduce the individual components of m6A methyltransferases and explain their close connections to each other. Then, we concentrate on the extensive biological functions of m6A methyltransferases, which include cell growth, nerve development, osteogenic differentiation, metabolism, cardiovascular system homeostasis, infection and immunity, and tumour progression. We summarize the currently unresolved problems in this research field and propose expectations for m6A methyltransferases as novel targets for preventive and curative strategies for disease treatment in the future.

中文翻译：

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m ⁶ A甲基转移酶的生物学功能

M6A甲基转移酶作为N6-甲基腺苷的作者，由于其动态调节生命过程而受到广泛关注。在这篇综述中，我们首先简要介绍m6A甲基转移酶的各个组成部分，并说明它们之间的紧密联系。然后，我们专注于m6A甲基转移酶的广泛生物学功能，包括细胞生长，神经发育，成骨分化，代谢，心血管系统稳态，感染和免疫以及肿瘤进展。我们总结了该研究领域中目前尚未解决的问题，并提出了对m6A甲基转移酶的期望，将其作为未来疾病治疗的预防和治疗策略的新目标。