Human Y chromosome reflects the evolutionary process of males. Male lineage tracing by Y chromosome is of great use in evolutionary, forensic, and anthropological studies when male samples exist or especially when the biological sample is a mixture of male and female individuals. Identifying the male lineage based on the specific distribution of Y haplogroups narrows down the investigation scope. Integrating previously published datasets with genotypes of Y chromosome short tandem repeats (Y-STRs) and high-resolution haplogroups (122 haplogroups in total), we developed YHP (Y Haplogroup Predictor), an open-access and user-friendly software package to predict haplogroups, compare the similarity, and conduct mismatch analysis of samples with Y-STR profiles. The software is available at Github (https://github.com/cissy123/YHP-Y-Haplogroup-Predictor-).

中文翻译：

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YHP：Y染色体单倍群预测子，用于基于Y-STR预测男性谱系

人的Y染色体反映了男性的进化过程。当存在男性样本时，特别是当生物学样本是男性和女性个体的混合物时，通过Y染色体追踪男性血统在进化，法医和人类学研究中非常有用。根据Y单倍群的具体分布识别男性血统会缩小研究范围。将以前发布的数据集与Y染色体短串联重复序列（Y-STRs）和高分辨率单倍群（总共122个单倍群）的基因型整合，我们开发了YHP（Y单倍群预测因子），这是一种开放式且易于使用的软件包，可以预测单倍型，比较相似性，并使用Y-STR谱图对样品进行错配分析。该软件可从Github（https://github.com/cissy123/YHP-Y-Haplogroup-Predictor-）获得。