The study goal was to provide an overview of antibiotic prescribing practices of Serbian dentists when treating endodontic infections and to disseminate the current ESE (European Society of Endodontology) recommendations to the study participants. A link to an online questionnaire was sent to 628 Serbian dentists whose email addresses were publicly available on the Internet, 158 of whom responded to the survey, resulting in a 25.16% response rate. The significance of possible associations was assessed via the Chi-squared test and Cramer’s V measure of association, with p < 0.05 considered as statistically significant. According to the study findings, 55.7% of respondents prescribed a 5-day antibiotic course. Moreover, Amoxicillin 500 mg was the first-choice antibiotic for 55.1% of the respondents, followed by Clindamycin 600 mg (18.4%). For patients allergic to penicillin, 61.4% of respondents prescribed Clindamycin. Statistically significant differences emerged only in relation to acute apical abscess with systemic involvement, whereby dentists aged 46–55 were least likely to prescribe antibiotics in these clinical situations (p = 0.04). Analyses further revealed that recommendations for safe antibiotic prescribing practices were not always followed, as in certain cases, patients were given antibiotics even when this was not indicated. These findings highlight the need for additional education on responsible antibiotic use to prevent bacterial resistance.

中文翻译：

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牙髓感染中的抗生素处方实践：塞尔维亚牙医的调查

该研究的目的是概述治疗牙髓感染时塞尔维亚牙医的抗生素处方操作，并向研究参与者传播当前的ESE（欧洲牙髓学会）建议。已向628名塞尔维亚牙医发送了一个在线调查问卷的链接，他们的电子邮件地址可以在Internet上公开获得，其中158位对此调查进行了回复，回复率为25.16％。通过卡方检验和Cramer's V关联度评估了可能关联的显着性，其中p<0.05被认为具有统计学意义。根据研究结果，55.7％的受访者开了5天抗生素疗程。此外，阿莫西林500毫克是55.1％的受访者的首选抗生素，其次是克林霉素600毫克（18.4％）。对于青霉素过敏的患者，有61.4％的受访者开了克林霉素。统计上的显着差异仅与系统性受累的急性根尖脓肿有关，因此在这些临床情况下，年龄46-55岁的牙医开抗生素的可能性最小（p= 0.04）。分析进一步表明，并非始终遵循关于安全的抗生素处方操作的建议，因为在某些情况下，即使未明确指出，患者也应给予抗生素。这些发现强调需要对负责任的抗生素使用进行进一步的教育，以预防细菌耐药。