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Comparison of standard versus population-specific handgrip strength cut-off points in the detection of probable sarcopenia after launch of EWGSOP2
The Aging Male ( IF 2.7 ) Pub Date : 2021-01-12
Gulistan Bahat, Cihan Kilic, Mustafa Altinkaynak, Mehmet Akif Karan

Abstract

Objective

We aimed to compare European Working Group on Sarcopenia in Older People (EWGSOP2)-suggested and population-specific handgrip strength (HGS) thresholds to detect probable sarcopenia and their associations with physical-performance measures and frailty.

Methods

A retrospective cross-sectional observational-study included geriatrics outpatients applied to a university-hospital. HGS, timed up and go test (TUG), and usual gait speed (UGS) were assessed. Frailty was screened by FRAIL-scale.

Results

A total of 1825 older adults were included (mean age, 74.5 + 7.0 years; 68.8% female). Prevalence of low-HGS were 12.2% by the EWGSOP2-recommended (27/16 kg) cut-offs and 37.5% by population-specific cut-offs (35/20 kg) (p<.001). When low-HGS was defined by EWGSOP2 suggested cut-offs, low-HGS was associated with impaired UGS, (odds ratio [OR] = 3.8, 95% confidence interval [CI]: 2.0–6.9, p<.001); impaired TUG, (OR = 4.6, 95% CI: 2.4–8.8, p<.001); and frailty (OR = 20.9, 95% CI: 8.3–53.0, p<.001). Similarly, low HGS determined by population-specific cut-off points was associated with impaired UGS (OR = 3.1, 95% CI: 2.1–6.9, p<.001); impaired TUG (OR = 6.0, 95% CI: 3.0–11.8, p<.001); and frailty (OR = 7.3, 95% CI: 4.1–13.0, p<.001).

Conclusions

Application of EWGSOP2-recommended standard HGS-cut-offs showed successful application in-practice. However, use of standard HGS cut-offs may result in underdiagnosis of probable sarcopenia. Therefore, we suggest that, whenever available, use of population-specific cut-offs for HGS may be better for correctly identifying older adults at risk.



中文翻译:

EWGSOP2发射后检测可能的肌肉减少症时标准和特定于人群的握力强度临界点的比较

摘要

目的

我们旨在比较欧洲老年人肌肉减少症工作组(EWGSOP2)建议的和特定人群的握力强度(HGS)阈值,以检测可能的肌肉减少症及其与身体表现指标和虚弱程度的关系。

方法

回顾性横断面观察性研究包括了应用于大学医院的老年病患者。HGS,定时和去测试(TUG)和通常的步态速度(UGS)进行了评估。通过FRAIL量表筛选脆弱性。

结果

总共包括1825个老年人(平均年龄74.5 + 7.0岁;女性68.8%)。通过EWGSOP2推荐的临界值(27/16千克),低HGS的患病率为12.2%,按人群特定的临界值(35/20千克)为37.5%(p <.001)。当EWGSOP2建议的临界值定义低HGS时,低HGS与UGS受损有关(赔率[OR] = 3.8,95%置信区间[CI]:2.0-6.9,p <.001);TUG受损((OR = 4.6,95%CI:2.4–8.8,p <.001);和脆弱(OR = 20.9,95%CI:8.3-53.0,p <.001)。同样,由人群特定的临界点确定的低HGS与UGS受损有关(OR = 3.1,95%CI:2.1–6.9,p <.001);TUG受损(OR = 6.0,95%CI:3.0–11.8,p<.001); 和脆弱(OR = 7.3,95%CI:4.1–13.0,p <.001)。

结论

推荐使用EWGSOP2推荐的标准HGS截止值在实践中取得成功。但是,使用标准HGS临界值可能会导致可能的少肌症的诊断不足。因此,我们建议,只要有可能,使用HGS的特定人群临界值可能会更好地正确识别有风险的老年人。

更新日期:2021-01-12
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