Abstract

Three new tryptamine derivatives diaporols T-V (1–3) were isolated by adding tryptamine into the culture of Diaporthe sp., a fungus obtained from the leaves of Rhizophora stylosa. The structures of these compounds were elucidated by NMR spectroscopy and high resolution mass spectroscopic data. Among them, compound 1 showed moderate cytotoxic activity against SW480 cancer cell with IC₅₀ 9.84 μM.

中文翻译：

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Diaporthe sp。通过生物转化产生色胺的衍生物。

摘要

三个新的色胺衍生物diaporols TV（1 - 3）通过加入到色胺的培养物中分离Diaporthe SP，从叶子上得到的真菌。红海榄。通过NMR光谱和高分辨率质谱数据阐明了这些化合物的结构。其中，化合物1对SW480癌细胞具有中等细胞毒活性，IC _50为9.84μM。