To investigate the need of allergic population for indoor environment quality, exposure effects of poor air quality on subjects with respiratory allergies were compared with those on healthy people, including perceptual responses, health symptoms, mental performance, and physiological responses. The experimental intervention was with and without ventilation at thermally neutral rooms, creating two exposure conditions indicated by CO₂ concentration ranges of 502 to 3297 ppm (2438 ± 1527 ppm) and 517 to 5687 ppm (3615 ± 1527 ppm). 63 subjects (32 allergic subjects and 31 non-allergic subjects) were exposed to both conditions for 3 hours. The main results suggested that, compared with healthy people, people with respiratory allergy seem to be more sensitive or less acceptable to reduced air quality polluted by occupants during instantaneous exposure. Besides, the allergic group performed worse in cognitive tests than non-allergic group. After 3 hours of continuous exposure, people with respiratory allergy reported stronger intensity of respiratory irritations and seemed to suffer more inflammation indicated by a higher level of interleukin 1L-1β.

中文翻译：

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暴露于降低的室内空气质量的呼吸道过敏患者的环境感知、心理表现和生理反应

为了调查过敏人群对室内环境质量的需求，比较了空气质量差对呼吸道过敏者与健康人的暴露影响，包括知觉反应、健康症状、心理表现和生理反应。实验干预是在热中性房间通风和不通风，创建两个暴露条件，由 CO ₂表示浓度范围为 502 至 3297 ppm (2438 ± 1527 ppm) 和 517 至 5687 ppm (3615 ± 1527 ppm)。63 名受试者（32 名过敏受试者和 31 名非过敏受试者）暴露于两种条件下 3 小时。主要结果表明，与健康人相比，患有呼吸道过敏症的人似乎对瞬间暴露于居住者所污染的空气质量降低更敏感或更不可接受。此外，过敏组在认知测试中的表现比非过敏组差。连续接触 3 小时后，患有呼吸道过敏症的人报告呼吸道刺激强度更强，并且似乎遭受更多炎症，这表明白细胞介素 1L-1β 水平更高。