Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths in the United States and compiles the most recent data on population‐based cancer occurrence. Incidence data (through 2017) were collected by the Surveillance, Epidemiology, and End Results Program; the National Program of Cancer Registries; and the North American Association of Central Cancer Registries. Mortality data (through 2018) were collected by the National Center for Health Statistics. In 2021, 1,898,160 new cancer cases and 608,570 cancer deaths are projected to occur in the United States. After increasing for most of the 20th century, the cancer death rate has fallen continuously from its peak in 1991 through 2018, for a total decline of 31%, because of reductions in smoking and improvements in early detection and treatment. This translates to 3.2 million fewer cancer deaths than would have occurred if peak rates had persisted. Long‐term declines in mortality for the 4 leading cancers have halted for prostate cancer and slowed for breast and colorectal cancers, but accelerated for lung cancer, which accounted for almost one‐half of the total mortality decline from 2014 to 2018. The pace of the annual decline in lung cancer mortality doubled from 3.1% during 2009 through 2013 to 5.5% during 2014 through 2018 in men, from 1.8% to 4.4% in women, and from 2.4% to 5% overall. This trend coincides with steady declines in incidence (2.2%‐2.3%) but rapid gains in survival specifically for nonsmall cell lung cancer (NSCLC). For example, NSCLC 2‐year relative survival increased from 34% for persons diagnosed during 2009 through 2010 to 42% during 2015 through 2016, including absolute increases of 5% to 6% for every stage of diagnosis; survival for small cell lung cancer remained at 14% to 15%. Improved treatment accelerated progress against lung cancer and drove a record drop in overall cancer mortality, despite slowing momentum for other common cancers.

中文翻译：

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癌症统计，2021

每年，美国癌症协会都会估计美国的新癌症病例和死亡人数，并汇编有关基于人群的癌症发生率的最新数据。发病率数据（到 2017 年）由监测、流行病学和最终结果计划收集；国家癌症登记计划；和北美中央癌症登记协会。死亡率数据（到 2018 年）由国家卫生统计中心收集。2021 年，美国预计将有 1,898,160 例新癌症病例和 608,570 例癌症死亡病例。在经历了 20 世纪大部分时间的增长之后，癌症死亡率从 1991 年的峰值持续下降到 2018 年，由于吸烟的减少和早期检测和治疗的改进，总下降了 31%。这转化为 3。如果峰值率持续下去，癌症死亡人数将减少 200 万。4 种主要癌症死亡率的长期下降在前列腺癌中停止，在乳腺癌和结直肠癌中放缓，但在肺癌中加速下降，占 2014 年至 2018 年总死亡率下降的近一半。男性肺癌死亡率的年下降率从 2009 年至 2013 年的 3.1% 翻番至 2014 年至 2018 年的 5.5%，女性从 1.8% 降至 4.4%，总体上从 2.4% 降至 5%。这一趋势与发病率稳步下降 (2.2%-2.3%) 相吻合，但特别是非小细胞肺癌 (NSCLC) 的生存率迅速提高。例如，NSCLC 2 年相对生存率从 2009 年至 2010 年期间诊断出的患者的 34% 增加到 2015 年至 2016 年期间的 42%，包括每个诊断阶段的绝对增加 5% 至 6%；小细胞肺癌的存活率保持在 14% 至 15%。尽管其他常见癌症的发展势头放缓，但改进的治疗方法加速了肺癌的进展，并推动了整体癌症死亡率的创纪录下降。