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The effects of novel coronavirus (SARS-CoV-2) infection on cardiovascular diseases and cardiopulmonary injuries
Stem Cell Research ( IF 0.8 ) Pub Date : 2021-01-12 , DOI: 10.1016/j.scr.2021.102168
Ni Li 1 , Linwen Zhu 2 , Lebo Sun 2 , Guofeng Shao 2
Affiliation  

COVID-19 caused by a novel coronavirus named SARS-CoV-2, can elites severe acute respiratory syndrome, severe lung injury, cardiac injury, and even death and became a worldwide pandemic. SARS-CoV-2 infection may result in cardiac injury via several mechanisms, including the expression of angiotensin-converting enzyme 2 (ACE2) receptor and leading to a cytokine storm, can elicit an exaggerated host immune response. This response contributes to multi-organ dysfunction. As an emerging infectious disease, there are limited data on the effects of this infection on patients with underlying cardiovascular comorbidities. In this review, we summarize the early-stage clinical experiences with COVID-19, with particular focus on patients with cardiovascular diseases and cardiopulmonary injuries, and explores potential available evidence regarding the association between COVID-19, and cardiovascular complications.



中文翻译:

新型冠状病毒(SARS-CoV-2)感染对心血管疾病和心肺损伤的影响

由一种名为 SARS-CoV-2 的新型冠状病毒引起的 COVID-19,可引发严重的急性呼吸系统综合症、严重的肺损伤、心脏损伤,甚至死亡,并成为全球大流行病。SARS-CoV-2 感染可能通过多种机制导致心脏损伤,包括血管紧张素转换酶 2 (ACE2) 受体的表达和导致细胞因子风暴,可引发过度的宿主免疫反应。这种反应会导致多器官功能障碍。作为一种新兴的传染病,关于这种感染对患有潜在心血管合并症的患者的影响的数据有限。在这篇综述中,我们总结了 COVID-19 的早期临床经验,特别关注患有心血管疾病和心肺损伤的患者,

更新日期:2021-01-21
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