Many studies highlight direct interactions between immune cells and enteric neurons, but whether immune signals can indirectly modulate enteric function through neurotransmitter regulation is poorly understood. In this issue of Immunity, Chen et al. reveal how IL-33 induces intestinal serotonin to promote gut motility.

中文翻译：

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IL-33 改变了我们对血清素的“直觉”

许多研究强调了免疫细胞和肠神经元之间的直接相互作用，但人们对免疫信号是否可以通过神经递质调节间接调节肠功能知之甚少。在本期Immunity中，Chen 等人。揭示 IL-33 如何诱导肠道血清素促进肠道蠕动。