The influence of soluble dietary fiber (SDF) obtained from sweet potato dregs on the diversity and structure of gut microbiota in mice were explored. Thirty-two male Kunming (KM) mice were randomly divided into the following four treatment groups for a period of 30 days: control group (control diet, GC), SDF low dose (0.5 g/(kg.d), LSDF), middle dose (1.5 g/(kg.d), MSDF), and high dose (2.5 g/(kg.d), HSDF). High-throughput sequencing was used to profile the structure of g gut microbiota in the cecum samples. Different contents of SDF from sweet potato dregs showed different effects on the intestinal flora of mice, in terms of OUT, phylum, genus and species levels. MSDF group could reduce the relative abundance of Desulfovibrio, Corynebacterium_1, and Aerococcus (harmful bacteria, which could induce the inflammatory disorders); It could also increase the abundance of Lactobacillus and Faecalibaculum (beneficial bacteria, which maintain the intestinal flora balance and have anti-inflammatory effects). However, LSDF and HSDF groups showed the opposite trends to the MSDF group. It might be because that the intestinal environment formed by the intake of 1.5 g/(kg.d) of SDF from sweet potato dregs in mice was relatively suitable for the growth of beneficial bacteria (e.g. Lactobacillus spp.), which is more conducive to the stability of intestinal flora. SDF from sweet potato dregs was effective on the intestinal flora of mice, and the MSDF group showed better effects than LSDF and HSDF.

探讨了甘薯渣中可溶性膳食纤维对小鼠肠道菌群多样性和结构的影响。将32只雄性昆明（KM）小鼠随机分为以下四个治疗组，持续30天：对照组（对照组饮食，GC），SDF低剂量（0.5 g /（kg.d），LSDF），中剂量（1.5 g /（kg.d），MSDF）和高剂量（2.5 g /（kg.d），HSDF）。高通量测序用于分析盲肠样品中肠道菌群的结构。来自甘薯渣的不同含量的SDF对OUT的肠道菌群表现出不同的影响，其门类，属和物种水平也不同。MSDF组可降低Desulfovibrio，Corynebacterium_1和Aerococcus的相对丰度（有害细菌，可能诱发炎症性疾病）；它也可以增加乳酸杆菌和Faecalibaculum（有益细菌，保持肠道菌群平衡并具有抗炎作用）的丰度。但是，LSDF和HSDF组显示出与MSDF组相反的趋势。可能是因为从老鼠的甘薯渣中摄取1.5 g /（kg.d）SDF形成的肠道环境相对适合有益细菌（例如，乳杆菌属）的生长。肠道菌群的稳定性。甘薯渣中的SDF对小鼠肠道菌群有效，而MSDF组的效果优于LSDF和HSDF。