Supplementation with anthocyanin-rich blackcurrant increases blood flow, cardiac output, and stroke volume at rest. It is not known whether cardiovascular responses can be replicated over longer timeframes in fed trained cyclists. In a randomized, double-blind, crossover design, 13 male trained cyclists (age 39 ± 10 years, $\dot{\mathrm{V}}{\mathrm{O}}_2\text{max}$ 55.3 ± 6.7 ml·kg⁻¹·min⁻¹) consumed two doses of New Zealand blackcurrant (NZBC) extract (300 and 600 mg/day for 1 week). Cardiovascular parameters were measured during rest and submaximal cycling (65% $\dot{\mathrm{V}}{\mathrm{O}}_2\text{max}$) on day 1 (D1), D4, and D7. Data were analyzed with an RM ANOVA using dose (placebo vs. 300 vs. 600 mg/day) by time point (D1, D4, and D7). Outcomes from placebo were averaged to determine the coefficient of variation within our experimental model, and 95% confidence interval (CI) was examined for differences between placebo and NZBC. There were no differences in cardiovascular responses at rest between conditions and between days. During submaximal exercise, no positive changes were observed on D1 and D4 after consuming NZBC extract. On D7, intake of 600 mg increased stroke volume (3.08 ml, 95% CI [−2.08, 8.26]; d = 0.16, p = .21), cardiac output (0.39 L/min, 95% CI [−1.39, .60]; d = 0.14, p = .40) (both +2.5%), and lowered total peripheral resistance by 6.5% (−0.46 mmHg·min/ml, 95% CI [−1.80, .89]; d = 0.18, p = .46). However, these changes were trivial and fell within the coefficient of variation of our study design. Therefore, we can conclude that NZBC extract was not effective in enhancing cardiovascular function during rest and submaximal exercise in endurance-trained fed cyclists.

补充富含花青素的黑醋栗可增加静息时的血流量、心输出量和每搏输出量。目前尚不清楚心血管反应是否可以在受过训练的骑自行车的人中在更长的时间范围内复制。在一项随机、双盲、交叉设计中，13 名受过训练的男性骑自行车者（年龄 39 ± 10 岁，$\dot{\mathrm{五}}{\mathrm{○}}_2\text{最大限度}$55.3 ± 6.7 ml·kg ^-1 ·min ^-1 ) 消耗了两剂新西兰黑醋栗 (NZBC) 提取物（300 和 600 毫克/天，持续 1 周）。在休息和次最大循环期间测量心血管参数（65%$\dot{\mathrm{五}}{\mathrm{○}}_2\text{最大限度}$) 在第 1 天 (D1)、D4 和 D7。在时间点（D1、D4 和 D7）使用剂量（安慰剂 vs. 300 vs. 600 mg/天）使用 RM ANOVA 分析数据。对安慰剂的结果进行平均以确定我们实验模型中的变异系数，并检查 95% 置信区间 (CI) 以了解安慰剂和 NZBC 之间的差异。在不同条件和不同天数之间，休息时的心血管反应没有差异。在次极量运动期间，服用 NBBC 提取物后 D1 和 D4 未观察到积极变化。在第 7 天，摄入 600 mg 增加每搏输出量（3.08 ml，95% CI [-2.08，8.26]；d  = 0.16，p  = .21），心输出量（0.39 L/min，95% CI [-1.39，. 60]；d  = 0.14，p = .40)（均为 +2.5%），并将总外周阻力降低 6.5%（-0.46 mmHg·min/ml，95% CI [-1.80, .89]；d  = 0.18，p  = .46）。然而，这些变化是微不足道的，属于我们研究设计的变异系数。因此，我们可以得出结论，NZBC 提取物不能有效增强受过耐力训练的喂食自行车运动员在休息和次极量运动期间的心血管功能。