Intrusive memories are common after trauma, and can cause significant distress. Interventions to prevent/reduce the occurrence of this core clinical feature of posttraumatic stress disorder are needed; they should be easy to deliver, readily disseminated and scalable. A novel one-session intervention by Iyadurai et al. 2018, Molecular Psychiatry, resulted in intrusion reduction over the subsequent week. Its feasibility in a different setting and longer-term effects (>1 month) need investigation. We conducted an exploratory open-label pilot randomised controlled trial (RCT) to investigate the feasibility and effects of a brief behavioural intervention to reduce intrusive memories in trauma-exposed patients in a Swedish hospital emergency department (ED). Participants (final N = 41) were randomly allocated to either intervention (including memory reminder cue then visuospatial cognitive task “Tetris” with mental rotation instructions) or active control (podcast) condition within 72 h of presenting to the ED (both conditions using their smartphone). Findings were examined descriptively. We estimated between-group effect sizes for the number of intrusive memories post-intervention at week 1 (primary outcome) and week 5 (secondary outcome). Compared to the control condition, participants in the intervention condition reported fewer intrusive memories of trauma, both at week 1 and week 5. Findings extend the previous evaluation in the UK. The intervention was readily implemented in a different international context, with a mixed trauma sample, with treatment gains maintained at 1 month and associated with some functional improvements. Findings inform future trials to evaluate the capacity of the cognitive task intervention to reduce the occurrence of intrusive memories after traumatic events.

侵入性记忆在创伤后很常见，并且会导致严重的痛苦。需要采取干预措施来预防/减少创伤后应激障碍这一核心临床特征的发生；它们应该易于交付、易于传播且可扩展。 Iyadurai 等人提出的一种新颖的单次干预。 2018 年，分子精神病学，导致接下来一周的入侵减少。其在不同环境下的可行性和长期影响（>1 个月）需要调查。我们进行了一项探索性开放标签试点随机对照试验（RCT），以调查瑞典医院急诊科（ED）的创伤暴露患者的短暂行为干预减少侵入性记忆的可行性和效果。参与者（最终N = 41）在向 ED 报告后 72 小时内被随机分配至干预组（包括记忆提醒提示，然后是视觉空间认知任务“俄罗斯方块”以及心理旋转指令）或主动控制（播客）条件组（两种条件均使用他们的手机）。对结果进行了描述性检查。我们估计了干预后第 1 周（主要结果）和第 5 周（次要结果）的侵入性记忆数量的组间效应大小。与对照条件相比，干预条件下的参与者在第 1 周和第 5 周报告的创伤侵入性记忆较少。研究结果扩展了之前在英国的评估。该干预措施很容易在不同的国际背景下实施，采用混合创伤样本，治疗效果维持在 1 个月，并与一些功能改善相关。 研究结果为未来评估认知任务干预减少创伤事件后侵入性记忆发生的能力的试验提供信息。