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The distribution of cellular turnover in the human body
Nature Medicine ( IF 58.7 ) Pub Date : 2021-01-11 , DOI: 10.1038/s41591-020-01182-9
Ron Sender 1 , Ron Milo 1
Affiliation  

We integrated ubiquity, mass and lifespan of all major cell types to achieve a comprehensive quantitative description of cellular turnover. We found a total cellular mass turnover of 80 ± 20 grams per day, dominated by blood cells and gut epithelial cells. In terms of cell numbers, close to 90% of the (0.33 ± 0.02) × 1012 cells per day turnover was blood cells.



中文翻译:

人体细胞更新分布

我们整合了所有主要细胞类型的普遍性、质量和寿命,以实现对细胞更新的全面定量描述。我们发现每天的总细胞质量周转量为 80 ± 20 克,主要是血细胞和肠上皮细胞。就细胞数量而言,接近 90% 的 (0.33 ± 0.02) × 10 12细胞/天周转是血细胞。

更新日期:2021-01-11
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