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Four new polyacetylenes from the roots of Saposhnikovia divaricata
Natural Product Research ( IF 1.9 ) Pub Date : 2021-01-10
Yan Sun, Yan-Ping Sun, Yan Liu, Juan Pan, Wei Guan, Xiao-Mao Li, Yuan Liu, Anam Naseem, Bing-You Yang, Hai-Xue Kuang

Abstract

Four new polyacetylene substances, sadivaethynes A–D, were isolated from the ethanol extract of the roots of Saposhnikovia divaricata (Turcz.) Schischk using repeated column chromatography. Structural elucidation of compounds 1–4 was established by 1D and 2D NMR spectra referring to the literature, together with high-resolution mass spectrometric analysis. All compounds were evaluated for cytotoxicity against two human cancer cell lines (MGC-803, Ishikawa) in vitro.



中文翻译:

Saposhnikovia divaricata根中的四种新的聚乙炔

摘要

使用重复柱色谱法从Saposhnikovia divaricata(Turcz。)Schischk根的乙醇提取物中分离出四种新的聚乙炔物质,sadivaethynes A–D 。参考文献,通过1D和2D NMR光谱以及高分辨率质谱分析,确定了化合物1-4的结构。在体外评估所有化合物对两种人癌细胞系(MGC-803,Ishikawa)的细胞毒性

更新日期:2021-01-11
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