Abstract Objectives Workplace‐based selective prevention of mental health problems currently relies on subjective evaluation of stress complaints. Hair cortisol captures chronic stress responses and could be a promising biomarker for the early identification of mental health problems. The objective was to provide an overview of the state‐of‐the‐art knowledge on the practical value of hair cortisol in the occupational setting. Methods We performed a scoping review of cross‐sectional and longitudinal studies in PubMed, Embase, and PsycINFO up to November 2019 assessing the relations of hair cortisol with work‐related stressors, perceived stress, and mental health outcomes in healthy workers. Results We found five longitudinal studies, of which two observed an increase in work‐related stressors to be associated with higher hair cortisol, one found a relation with lower hair cortisol and one did not find a relationship. Findings of cross‐sectional studies were also mixed. The one available longitudinal study regarding mental health showed that hair cortisol was not related to depressive symptoms. Conclusions Hair cortisol measurement within occupational health research is still in its early stage and more longitudinal studies are urgently needed to clarify its relationship with work‐related stressors and perceived stress before hair cortisol can be used to identify workers at risk for mental health problems.

中文翻译：

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使用头发皮质醇测量职业保健中慢性压力的潜力；范围审查

摘要目标基于工作场所的心理健康问题选择性预防目前依赖于对压力投诉的主观评价。头发皮质醇可以捕捉慢性压力反应，并可能成为早期识别心理健康问题的有前途的生物标志物。目的是概述有关头发皮质醇在职业环境中的实用价值的最新知识。方法 我们对截至 2019 年 11 月的 PubMed、Embase 和 PsycINFO 中的横断面和纵向研究进行了范围审查，评估了健康工人的头发皮质醇与工作相关压力源、感知压力和心理健康结果的关系。结果 我们发现了五项纵向研究，其中两项观察到工作相关压力源的增加与较高的头发皮质醇有关，一个发现与较低的头发皮质醇有关，一个没有发现关系。横断面研究的结果也参差不齐。一项关于心理健康的纵向研究表明，头发皮质醇与抑郁症状无关。结论 职业健康研究中的头发皮质醇测量仍处于早期阶段，迫切需要更多的纵向研究来阐明其与工作相关压力源和感知压力的关系，然后才能使用头发皮质醇来识别有心理健康问题风险的工人。