A four factor three level Box-Behnken design (BBD) was analysed to define the photocatalytic degradation of atenolol in an aqueous solution in slurry mode. The four different process variables under consideration in BBD model included synthesized Graphene Oxide-ZnO (GO/ZnO) catalyst dose, pH, Atenolol concentration and variation of light intensity. The model predicted the optimum value for maximum degradation rate with conditions set at 1.2 g/L catalyst concentration, pH of 4, 25 mg/l substrate concentration and 940 W light intensity. The first-order reaction rate at this optimum reaction condition is 0.845 min⁻¹. The substrate concentration and light intensity showed highest positive effect on atenolol degradation while pH and catalyst concentration showed negative effect towards atenolol degradation. The data obtained from 29 experiments suggest that maximum rate of reaction (0.783 min⁻¹) has been achieved within 1 h under solar irradiation at pH 6.5 using 25 ppm atenolol concentration and catalyst concentration of 1.25 g/L at light intensity of 1000 W. The model shows high correlation (R² > 0.953) between experimental and predicted values. It was observed that the rate of degradation with GO/ZnO composite is faster when compared to Graphene/TiO₂ composite.

分析了四因素三能级Box-Behnken设计（BBD），以定义在浆液模式下阿替洛尔在水溶液中的光催化降解。BBD模型中考虑的四个不同过程变量包括合成的氧化石墨烯-ZnO（GO / ZnO）催化剂剂量，pH，阿替洛尔浓度和光强度变化。该模型在以下条件下预测最大降解速率的最佳值：催化剂浓度为1.2 g / L，pH为4，底物浓度为25 mg / l，光强度为940W。在该最佳反应条件下的一级反应速率为0.845 min ^-1。底物浓度和光强度对阿替洛尔的降解表现出最大的积极影响，而pH和催化剂浓度对阿替洛尔的降解表现出不利的影响。从29个实验获得的数据表明，在25％的阿替洛尔浓度和1.25 g / L的催化剂浓度，光强度为1000 W的条件下，在pH值为6.5的太阳辐射下，在1小时内已达到最大反应速率（0.783 min ^-1）。该模型显示出实验值和预测值之间的高度相关性（R ² > 0.953）。观察到，与石墨烯/ TiO ₂复合材料相比，GO / ZnO复合材料的降解速度更快。