Dietary modification would be the most translatable, cost-efficient, and, likely, the safest approach available that can reduce the reliance on pharmaceutical treatments for treating acute or chronic neurological disorders. A wide variety of evidence suggests that the ketogenic diet (KD) could have beneficial effects in acute traumatic events, such as spinal cord injury and traumatic brain injury. Review of existing human and animal studies revealed that KD can improve motor neuro-recovery, gray matter sparing, pain thresholds, and neuroinflammation and decrease depression. Although the exact mechanism by which the KD provides neuroprotection is not fully understood, its effects on cellular energetics, mitochondria function and inflammation are likely to have a role.

饮食调整将是最可转化的、最具成本效益的，并且可能是最安全的方法，可以减少对治疗急性或慢性神经系统疾病的药物治疗的依赖。各种各样的证据表明，生酮饮食 (KD) 可能对急性创伤事件产生有益的影响，例如脊髓损伤和创伤性脑损伤。回顾现有的人类和动物研究表明，KD 可以改善运动神经恢复、灰质保留、疼痛阈值和神经炎症，并减少抑郁症。尽管 KD 提供神经保护的确切机制尚不完全清楚，但它对细胞能量学、线粒体功能和炎症的影响可能会起作用。