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Hypoxia: Uncharged tRNA to the Rescue!
Current Biology ( IF 8.1 ) Pub Date : 2021-01-11 , DOI: 10.1016/j.cub.2020.10.067
Thomas E Mulroney 1 , Tuija Pöyry 1 , Anne E Willis 1
Affiliation  

A new study has identified genes that protect Caenorhabditis elegans from hypoxic stress. Genomic approaches and whole-organism proteomics reveal a regulatory interaction between a threonyl-tRNA synthetase and ribosome biogenesis that modulates global translation and hypoxic sensitivity.



中文翻译:

缺氧:解救不带电的 tRNA!

一项新的研究确定了保护秀丽隐杆线虫免受缺氧压力的基因。基因组学方法和全生物体蛋白质组学揭示了苏氨酰-tRNA 合成酶和核糖体生物合成之间的调节相互作用,从而调节全局翻译和缺氧敏感性。

更新日期:2021-01-11
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