Centromeres, the chromosomal loci that ensure chromosome segregation by directing kinetochore assembly, are typically marked by the histone CENP-A. A study in CENP-A-deficient insects finds that virtually any chromosomal region with low nucleosome turnover can assemble kinetochores, highlighting the extraordinary plasticity of holocentromeres.

中文翻译：

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细胞分裂：染色质动力学形状昆虫昆虫着丝粒

着丝粒通常是由组蛋白CENP-A标记，它是通过指导动粒组装来确保染色体分离的染色体基因座。一项针对CENP-A缺陷型昆虫的研究发现，几乎任何核小体周转率较低的染色体区域都可以组装动植物，从而突显了整体着丝粒的非凡可塑性。