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COVID-19: Analysis of Drug Repositioning Practice
Pharmaceutical Chemistry Journal ( IF 0.9 ) Pub Date : 2021-01-01 , DOI: 10.1007/s11094-021-02308-0 P I Savosina 1 , D S Druzhilovskii 1 , V V Poroikov 1
Pharmaceutical Chemistry Journal ( IF 0.9 ) Pub Date : 2021-01-01 , DOI: 10.1007/s11094-021-02308-0 P I Savosina 1 , D S Druzhilovskii 1 , V V Poroikov 1
Affiliation
An outbreak of a new coronavirus disease (COVID-19) in China in December 2019 became the epicenter for the spread of a global pandemic. The SARS-CoV-2 coronavirus causes a cascade of respiratory diseases similar to severe acute respiratory syndrome (SARS). Currently, there is no effective, specific, and safe treatment for COVID-19 to suppress the virus in the human body. The present study searched for pharmacological substances with antiviral activity for possible drug repositioning based on experimental and theoretical information in a series of publications on in vitro assays of agents against SARS-CoV-2. An analysis identified 46 well-known pharmaceutical substances that could be used for drug repositioning to create a therapy for COVID-19.
更新日期：2021-01-01
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