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Camps Reaction and Related Cyclizations
Russian Journal of Organic Chemistry ( IF 0.8 ) Pub Date : 2021-01-11 , DOI: 10.1134/s1070428020110019
A. S. Fisyuk , A. S. Kostyuchenko , D. S. Goncharov

Abstract

The review presents analysis of the literature on the intramolecular cyclization of N-(2-acylaryl)amides, known as the Camps reaction, as well as close analogs of these compounds, N-(3-oxoalkenyl)- and N-(3-oxoalkyl)amides, which contain an amide and a carbonyl groups and react by the aldol–crotonic type. The potential, limitations, and regularities of these reactions leading to quinoline-2(1H)-ones, quinoline-4(1H)-ones, pyridin-2-ones, pyridin-4-ones, as well as their hydrogenated derivatives are highlighted.



中文翻译:

营地反应和相关环化

摘要

这篇综述介绍了有关N-(2-酰基芳基)酰胺分子内环化(称为Camps反应)以及这些化合物的近类似物N-(3-氧代烯基)-和N-(3-氧代烷基)酰胺,含有一个酰胺和一个羰基,并通过羟醛-巴豆型反应。这些反应的潜在性,局限性和规律性导致喹啉-2(1 H)-one,喹啉-4(1 H)-one,吡啶-2-酮,吡啶4--4-酮及其氢化衍生物突出显示。

更新日期:2021-01-11
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