In the past 40 years, scientific research has shown how Whole Body Vibration concept represents a strong stimulus for the whole organism. Low (<30 Hz), medium (30–80 Hz), and high (>80 Hz) frequency vibrations can have both positive and negative effects, depending on the oscillation type and duration of exposure to which the body is subjected. However, very little is known about the effects of vibratory training on the brain. In this regard, we verified whether three vibratory training protocols, differing in terms of vibration frequency and exposure time to vibration, could modulate synaptic plasticity in an experimental mouse model, by extracellular recordings in vitro in hippocampal slices of mice of 4 and 24 months old. Our results showed that vibratory training can modulate synaptic plasticity differently, depending on the protocol used, and that the best effects are related to the training protocol characterized by a low vibration frequency and a longer recovery time. Future studies will aim to understand the brain responses to various types of vibratory training and to explore the underlying mechanisms, also evaluating the presence of any structural and functional changes due to vibratory training.

中文翻译：

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振动训练对年轻小鼠和老年小鼠的突触可塑性的调节

在过去的40年中，科学研究表明“全身振动”概念如何对整个生物体产生强烈的刺激作用。低（<30 Hz），中（30-80 Hz）和高（> 80 Hz）振动会产生正面和负面影响，具体取决于人体的振动类型和暴露时间。但是，关于振动训练对大脑的影响知之甚少。在这方面，我们通过在4和24个月大的小鼠海马切片中进行体外细胞外记录，验证了三种振动训练方案（在振动频率和振动暴露时间方面是否不同）是否可以调节实验小鼠模型中的突触可塑性。 。我们的结果表明，根据所使用的协议，振动训练可以不同地调节突触可塑性，最佳效果与训练方案有关，该方案的特点是振动频率低，恢复时间更长。未来的研究将旨在了解大脑对各种类型的振动训练的反应，并探索其潜在机制，并评估由于振动训练而导致的任何结构和功能变化的存在。