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An overview of developmental dysregulation of autonomic control in infants
Birth Defects Research ( IF 2.1 ) Pub Date : 2021-01-09 , DOI: 10.1002/bdr2.1855
Adulzir E Altamirano 1, 2 , Christopher G Wilson 2
Affiliation  

In this short review, we provide an overview of developmental disorders causing autonomic nervous system dysregulation. We briefly discuss perinatal conditions that adversely impact developmental outcomes including apnea of prematurity, sudden infant death syndrome, and Rett syndrome. We provide a brief clinical description, an overview of known or hypothesized mechanisms for the disorder, and current standard of practice for treatment of each condition. Additionally, we consider preventative measures and complications of these disorders to provide further insight into the pathogenesis of specific autonomic dysregulation in neonates. The goal of this short review is to provide an updated understanding of the impact of autonomic dysregulation on development of brainstem circuits and to briefly highlight promising future treatment options and controversies.

中文翻译:

婴儿自主神经控制发育失调的概述

在这篇简短的评论中,我们概述了导致自主神经系统失调的发育障碍。我们简要讨论了对发育结果产生不利影响的围产期疾病,包括早产儿呼吸暂停、婴儿猝死综合征和 Rett 综合征。我们提供简短的临床描述、对该疾病已知或假设机制的概述,以及治疗每种疾病的当前实践标准。此外,我们考虑了这些疾病的预防措施和并发症,以进一步了解新生儿特定自主神经失调的发病机制。
更新日期:2021-01-09
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