1,4-Dihydropyridines are a class of drugs with a wide range of biological activities and pharmacological effects. However, there are few reports on its optical activity, especially its application on fluorescent CN^- probe. In this experiment, we designed and synthesized a fluorescent probe based on 1,4-dihydropyridines to detect CN^-. Interestingly, the probe exhibited outstanding properties such as 100% water soluble, near infrared, ratiometric, fast response, high selectivity and anti-interference ability for other ions. The color change indicated that the probe can be used for naked eye identification. In particular, the probe showed a super large fluorescent emission peak shift (260 nm). In addition, the reaction mechanism of the probe has been studied by ¹H NMR titration, high resolution mass spectrometry and theoretical calculations.

1,4-二氢吡啶类是一类具有广泛的生物活性和药理作用的药物。不过，也有它的光学活性，特别是其对荧光CN应用鲜有报道^-探头。在这个实验中，我们设计并合成了基于1,4-二氢吡啶来检测CN荧光探针^- 。有趣的是，该探针表现出出色的性能，例如100％水溶性，近红外，比例测定，快速响应，高选择性和对其他离子的抗干扰能力。颜色变化表明该探头可用于肉眼识别。特别地，该探针显示出超大的荧光发射峰位移（260nm）。另外，对探针的反应机理进行了研究¹1 H NMR滴定，高分辨率质谱和理论计算。