Age-related resistance (ARR), or ontogenic resistance, is associated with host developmental stages. Winter squash fruit (Cucurbita moschata) develops resistance to the oomycete plant pathogen, Phytophthora capsici, as they mature. ARR in winter squash to P. capsici could be exploited to assist growers in limiting crop loss due to fruit rot. The objective of this study was to determine whether preformed or pathogen-induced antifungal activity during fruit development is correlated with ARR. We examined fruit peel methanol/ethanol extracts of three cultivars of C. moschata at different developmental stages with and without P. capsici inoculation. Results indicated the presence of compounds with antifungal activity in all fruit ages tested, but the antifungal activity decreased with age indicating a lack of association between preformed antifungal activity and ARR in winter squash. In addition, no significant change was detected in the antifungal activity among fruit ages that were inoculated with P. capsici and examined at different times post inoculation, suggesting no association between the induced antifungal activity and ARR in winter squash.

与年龄相关的抗性（ARR）或本体抗性与宿主发育阶段有关。冬南瓜果实（Cucurbita moschata）在成熟时对卵菌植物病原体疫霉菌（Phytophthora capsici）产生抗药性。可以利用冬季南瓜到辣椒的ARR来帮助种植者限制因果实腐烂而造成的作物损失。这项研究的目的是确定水果发育过程中预先形成的或病原体诱导的抗真菌活性是否与ARR相关。我们检查果皮甲醇/乙醇中的3个品种提取物C.南瓜在有和没有不同发育阶段辣椒疫霉接种。结果表明在所有测试的果实年龄中都存在具有抗真菌活性的化合物，但是抗真菌活性随年龄的增长而降低，表明冬南瓜中预先形成的抗真菌活性与ARR之间缺乏关联。此外，在接种辣椒后并在接种后的不同时间检查的果实年龄之间，未检测到抗真菌活性的显着变化，表明诱导的抗真菌活性与西葫芦之间没有相关性。