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Soluble DC-SIGN isoforms: Ligands with unknown functions - A mini-review
Microbial Pathogenesis ( IF 3.3 ) Pub Date : 2021-01-08 , DOI: 10.1016/j.micpath.2021.104731
Lailah Horácio Sales Pereira 1 , Amanda do Carmo Alves 2 , Jaqueline Maria Siqueira Ferreira 3 , Luciana Lara Dos Santos 2
Affiliation  

The present study aimed to perform a mini-review of the complete soluble isoforms of Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin (sDC-SIGN), their functions, and their correlation with diseases. The present review reveals the lack of studies regarding these soluble isoforms and poor understanding of the importance of the topic, considering the concordant findings on the relevant influence of sDC-SIGN in the viral and bacterial infection process, in addition to its possible use as a cancer marker.



中文翻译:

可溶性DC-SIGN同工型:功能未知的配体-小型综述

本研究旨在对树突状细胞特异的细胞间粘附分子-3-抓取非整联蛋白(sDC-SIGN)的完整可溶性同工型,其功能及其与疾病的关系进行迷你综述。本综述揭示了缺乏关于这些可溶性同工型的研究,并且对该主题的重要性缺乏了解,考虑到关于sDC-SIGN在病毒和细菌感染过程中的相关影响的一致发现,此外还可能将其用作药物。癌症标记。

更新日期:2021-01-13
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