β-type titanium alloys have attracted much attention as implant materials because of their low elastic modulus and high strength, which is closer to human bones and can avoid the problem of stress fielding and extend the lifetime of prosthetics. However, other issues, such as the infection or inflammation postimplantation, still trouble the titanium alloy's clinical application. In this paper, we developed a novel near β-titanium alloy (Ti-13Nb-13Zr-13Ag, TNZA) with low elastic modulus and strong antibacterial ability by the addition of Ag element followed by proper microstructure controlling, which could reduce the stress shielding and bacterial infections simultaneously. The microstructure, mechanical properties, corrosion resistance, antibacterial properties and cell toxicity were studied using SEM, electrochemical testing, mechanical test and cell tests. The results have demonstrated that TNZA alloy exhibited an elastic modulus of 75−87 GPa and a strong antibacterial ability (up to 98 % reduction) and good biocompatibility. Moreover, it was also shown that this alloy's corrosion resistance was better than that of Ti-13Nb-13Zr. All the results suggested that Ti-13Nb-13Zr-13Ag might be a competitive biomedical titanium alloy.

β型钛合金的弹性模量低，强度高，更贴近人体骨骼，可以避免应力场的问题，延长了假体的使用寿命，因此作为植入材料备受关注。但是，其他问题，例如植入后的感染或炎症，仍然困扰着钛合金的临床应用。在本文中，我们通过添加Ag元素并进行适当的微结构控制，开发了一种具有低弹性模量和强抗菌能力的新型近β钛合金（Ti-13Nb-13Zr-13Ag，TNZA），可以减少应力屏蔽和细菌感染同时发生。使用扫描电镜，电化学测试，研究了合金的微观结构，力学性能，耐腐蚀性，抗菌性能和细胞毒性。机械测试和电池测试。结果表明，TNZA合金的弹性模量为75-87 GPa，具有很强的抗菌能力（降低了98％）和良好的生物相容性。此外，还表明该合金的耐腐蚀性优于Ti-13Nb-13Zr。所有结果表明，Ti-13Nb-13Zr-13Ag可能是具有竞争力的生物医学钛合金。