A 3-year-old intact male African pygmy hedgehog (Atelerix albiventris) was found dead shortly after clinical onset of screaming, aerophagia and lethargy. On gross examination, the spleen was dark red and friable, and the liver was markedly enlarged with a prominent lobular pattern and multiple white nodules. Histopathological examination of liver and spleen revealed dense infiltrates of highly pleomorphic neoplastic, round to polyhedral cells with overt erythrophagocytosis. Similar neoplastic cells were found in the sinuses of the abdominal lymph nodes and in blood vessels in the heart, lung, brain and kidneys. Immunolabelling for CD204 confirmed the histiocytic origin of the neoplastic cells. To our knowledge, this is the first report of a disseminated haemophagocytic histiocytic sarcoma in a hedgehog.

一只 3 岁的完整雄性非洲侏儒刺猬 ( Atelerix albiventris ) 在临床出现尖叫、吞气和嗜睡后不久被发现死亡。大体检查，脾脏呈暗红色且易碎，肝脏明显肿大，呈明显的小叶状图案和多个白色结节。肝脏和脾脏的组织病理学检查显示高度多形性肿瘤的密集浸润，圆形至多面体细胞，具有明显的红细胞吞噬作用。在腹部淋巴结的鼻窦和心脏、肺、脑和肾脏的血管中发现了类似的肿瘤细胞。CD204 的免疫标记证实了肿瘤细胞的组织细胞起源。据我们所知，这是第一份关于刺猬中播散性噬血细胞组织细胞肉瘤的报告。