Purpose

To report on a second-generation prototype contact lens (modified lens) with enhanced optics to correct coma aberration and compare its performance with that of the prototype contact lens (conventional lens) used to optimise correction of coma aberration in keratoconus (KC).

Methods

Both lenses were designed as a set of standardised soft contact lenses (SCLs) with asymmetric powers along the posterior surface. The modified lens differs from the conventional lens in that the optical zone is decentred superiorly by 0.7 mm. The on-eye performance was compared between the SCLs and no-lens wearing in terms of manifest refraction, corrected distance visual acuity (CDVA), ocular aberrations, subjective quality of vision, and on-eye lens position relative to the pupil.

Results

Thirty-four KC eyes were included. SCLs significantly decreased coma aberration compared to no-lens wear (none, 0.68 ± 0.27 μm; conventional lens, 0.37 ± 0.28 μm; modified lens, 0.19 ± 0.15 μm; P < 0.001), with the reduction in coma aberration being significantly greater with the modified lens than with the conventional lens (P = 0.018). No significant difference in manifest refraction or CDVA was found among the three conditions. Quality of vision was significantly better with the modified lens than with no SCL wear (P < 0.05) but no differences were found between the SCLs. The on-eye optical center position relative to the pupil was closer to the pupil centre using the modified lens than the conventional lens (P < 0.001).

Conclusion

Optimisation of the location of the optical zone in a standardised asymmetric SCL improves correction of coma aberrations and on-eye optical centration.

中文翻译：

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新型软性隐形眼镜优化圆锥角膜彗差矫正

目的

报告第二代原型隐形眼镜（改良镜片），具有增强光学功能以校正彗形像差，并将其性能与用于优化圆锥角膜（KC）彗形像差校正的原型隐形眼镜（传统镜片）的性能进行比较。

方法

两种镜片均设计为一组标准化的软性隐形眼镜 (SCL)，其后表面具有不对称的屈光力。改进后的镜片与传统镜片的不同之处在于，其光学区域偏心了 0.7 毫米。在明显屈光度、矫正远视力 (CDVA)、眼像差、主观视觉质量和眼内镜片相对于瞳孔的位置方面，比较了 SCL 和不佩戴镜片的眼上性能。

结果

包括 34 只 KC 眼。与无镜片佩戴相比，SCL 显着降低了彗差（无，0.68 ± 0.27 μm；常规镜片，0.37 ± 0.28 μm；改良镜片，0.19 ± 0.15 μm；P < 0.001），彗差的降低显着更大修改后的镜片与传统镜片相比（P = 0.018）。在三种情况下，没有发现明显屈光度或 CDVA 的显着差异。与没有佩戴 SCL 的镜片相比，改良镜片的视觉质量明显更好（P < 0.05），但在SCL之间没有发现差异。与传统镜片相比，使用改良镜片的眼上光学中心相对于瞳孔的位置更靠近瞳孔中心（P < 0.001）。

结论

在标准化的非对称 SCL 中优化光学区的位置可以改善彗形像差和眼睛光学中心的校正。