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The storage of skull bone flaps for autologous cranioplasty: literature review
Cell and Tissue Banking ( IF 1.4 ) Pub Date : 2021-01-09 , DOI: 10.1007/s10561-020-09897-2
Vicente Mirabet 1 , Daniel García 2 , Nuria Yagüe 1 , Luis Roberto Larrea 1 , Cristina Arbona 1 , Carlos Botella 2
Affiliation  

The use of autologous bone flap for cranioplasty after decompressive craniectomy is a widely used strategy that allows alleviating health expenses. When the patient has recovered from the primary insult, the cranioplasty restores protection and cosmesis, recovering fluid dynamics and improving neurological status. During this time, the bone flap must be stored, but there is a lack of standardization of tissue banking practices for this aim. In this work, we have reviewed the literature on tissue processing and storage practices. Most of the published articles are focused from a strictly clinical and surgical point of view, paying less attention to issues related to tissue manipulation. When bone resorption is avoided and the risk of infection is controlled, the autograft represents the most efficient choice, with the lowest risk of complication. Otherwise, depending on the degree of involvement, the patient may have to undergo new surgery, assuming further risks and higher healthcare costs. Therefore, tissue banks must implement protocols to provide products with the highest possible clinical effectiveness, without compromising safety. With a centralised management of tissue banking practices there may be a more uniform approach, thus facilitating the standardization of procedures and guidelines.



中文翻译:

自体颅骨成形术颅骨瓣的储存:文献综述

在去骨瓣减压术后使用自体骨瓣进行颅骨成形术是一种广泛使用的策略,可以减轻医疗费用。当患者从最初的损伤中恢复时,颅骨成形术会恢复保护和美容,恢复流体动力学并改善神经状态。在此期间,必须储存骨瓣,但为此目的缺乏组织储存实践的标准化。在这项工作中,我们回顾了有关组织处理和储存实践的文献。大多数已发表的文章都从严格的临床和外科角度出发,较少关注与组织操作相关的问题。当避免骨吸收并控制感染风险时,自体移植是最有效的选择,并发症风险最低。否则,根据受累程度,患者可能不得不接受新的手术,承担更大的风险和更高的医疗费用。因此,组织库必须实施协议,在不影响安全性的情况下提供具有最高临床有效性的产品。通过对组织库实践进行集中管理,可能会有更统一的方法,从而促进程序和指南的标准化。

更新日期:2021-01-10
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