The emerging SARS-CoV-2 viral disease (COVID-19) has caused a global health alert due to its high rate of infection and mortality in individuals with chronic cardiovascular comorbidities, in addition to generating complex clinical conditions. This has forced the scientific community to explore different strategies that allow combating this viral infection as well as treating life-threatening systemic effect of the infection on the individual. In this work, we have reviewed the most recent scientific evidence to provide a comprehensive panorama regarding the biotechnological strategies that have been proposed to combat this new viral infection. We have focused our analysis on vaccine production, nanotechnology applications, repurposing of know drugs for unrelated pathologies, and the search for bioactive molecules obtained from natural products. The goals include safely use as potential prophylactic or therapeutic treatments, based on in silico and in vivo studies, including clinical trials around the world for the correct and timely diagnosis of the infection. This review aims to highlight the development of new ideas that can decrease the time lines for research output and improve research quality while at the same time, keeping in mind the efficacy and safety aspects of these potential biotechnological strategies.

新出现的 SARS-CoV-2 病毒性疾病 (COVID-19) 因其在患有慢性心血管合并症的个体中的高感染率和死亡率以及产生复杂的临床状况而引起了全球健康警报。这迫使科学界探索不同的策略，以对抗这种病毒感染，并治疗感染对个体危及生命的全身性影响。在这项工作中，我们回顾了最新的科学证据，以提供有关为对抗这种新病毒感染而提出的生物技术策略的全面全景。我们的分析重点是疫苗生产、纳米技术应用、已知药物用于不相关疾病的再利用，以及从天然产物中寻找生物活性分子。目标包括基于计算机和体内研究（包括世界各地的临床试验）安全地用作潜在的预防或治疗方法，以正确和及时地诊断感染。本综述旨在强调新想法的发展，这些新想法可以缩短研究产出的时间并提高研究质量，同时牢记这些潜在生物技术策略的有效性和安全性。