The sit-to-stand (STS) test has been deployed as surrogate measures of strength or physical performance in sarcopenia diagnosis. This study examines the relationship of two common STS variants – Five Times Sit-to-Stand Test (5TSTS) and 30 s Chair Stand Test (30CST) – with grip strength, muscle mass and functional measures, and their impact on sarcopenia prevalence in community-dwelling older adults. This is a cross-sectional analysis of 887 community-dwelling adults aged ≥50 years. Participants completed a battery of physical fitness tests - 5TSTS, 30CST, grip strength, gait speed, Timed-Up-and-Go (TUG) for dynamic balance and six-minute walk test (6MWT) for cardiorespiratory endurance. Muscle mass was measured using multi-frequency segmental bioelectrical impedance analysis (BIA). We performed correlation analysis between STS performance and other fitness measures and muscle mass, followed by multiple linear regression for the independent determinants of STS performance. Mean participant age was 67.3±7 years, with female predominance (72.9%). STS tests exhibited weak correlations with grip strength (30CST, r = 0.290; 5TSTS, r = − 0.242; both p< 0.01), and stronger correlations with gait speed (30CST, r = 0.517; 5TSTS, r = − 0.533; both p< 0.01), endurance (30CST, r = 0.558; 5TSTS, r = − 0.531; both p < 0.01) and dynamic balance (30CST, r = − 0.501; 5TSTS, r = 0.646; both p< 0.01). Muscle mass correlated with grip strength but not STS. In multiple regression analysis, all fitness measures were independently associated with 30CST performance. Performance in both STS tests remained independent of muscle mass. There was no significant difference in prevalence of possible sarcopenia diagnosis using grip strength or STS (30CST, 25.0%; 5TSTS, 22.1%; grip strength, 22.3%; p = 0.276). When both measures are used, prevalence is significantly higher (42.0%; p = 0.276). Prevalence of confirmed sarcopenia with inclusion of muscle mass was significantly lower using STS compared with grip strength (30CST, 4.6%; 5TSTS, 4.1% vs. grip strength, 7.1%; p< 0.05). In the sarcopenia construct, STS tests better represents muscle physical performance rather than muscle strength. Different subsets of population with possible sarcopenia are identified depending on the test used. The lack of association of STS performance with muscle mass results in a lower prevalence of confirmed sarcopenia compared with grip strength, but may better reflect changes in muscle quality.

中文翻译：

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社区居住老年人的坐站测试表现与功能健康和肌肉减少症诊断的测量相关


坐站（STS）测试已被用作肌肉减少症诊断中力量或身体表现的替代指标。本研究探讨了两种常见的 STS 变体——五次坐站测试 (5TSTS) 和 30 秒椅子站立测试 (30CST)——与握力、肌肉质量和功能测量的关系，及其对社区肌少症患病率的影响- 居住的老年人。这是对 887 名 50 岁以上社区居民的横断面分析。参与者完成了一系列体能测试 - 5TSTS、30CST、握力、步态速度、动态平衡计时起立行走 (TUG) 和心肺耐力六分钟步行测试 (6MWT)。使用多频率节段生物电阻抗分析（BIA）测量肌肉质量。我们对 STS 表现与其他健身指标和肌肉质量之间进行了相关分析，然后对 STS 表现的独立决定因素进行了多元线性回归。参与者的平均年龄为 67.3±7 岁，其中女性占多数（72.9%）。 STS 测试与握力的相关性较弱（30CST，r = 0.290；5TSTS，r = − 0.242；均 p < 0.01），而与步态速度的相关性较强（30CST，r = 0.517；5TSTS，r = − 0.533；均 p < 0.01）、耐力（30CST，r = 0.558；5TSTS，r = − 0.531；均 p < 0.01）和动态平衡（30CST，r = − 0.501；5TSTS，r = 0.646；均 p < 0.01）。肌肉质量与握力相关，但与 STS 无关。在多元回归分析中，所有健身指标均与 30CST 表现独立相关。两项 STS 测试中的表现仍然与肌肉质量无关。使用握力或 STS 诊断可能的肌少症的患病率没有显着差异（30CST，25.0%；5TSTS，22.1%；握力，22.3%； p = 0.276）。当同时使用这两种措施时，患病率显着更高（42.0%；p = 0.276）。与握力相比，使用 STS 确认的肌肉减少症（包括肌肉质量）的患病率显着降低（30CST，4.6%；5TSTS，4.1% 对比握力，7.1%；p < 0.05）。在肌少症结构中，STS 测试更好地代表肌肉的物理性能而不是肌肉力量。根据所使用的测试，确定可能患有肌少症的不同人群子集。与握力相比，STS 表现与肌肉质量缺乏关联导致确诊的肌少症患病率较低，但可能更好地反映肌肉质量的变化。