Summary KNIT is a web application that provides a hierarchical, directed graph on how a set of genes is connected to a particular gene of interest. Its primary aim is to aid researchers in discerning direct from indirect effects that a gene might have on the expression of other genes and molecular pathways, a very common problem in omics analysis. As such, KNIT provides deep contextual information for experiments where gene or protein expression might be changed, such as gene knock-out and overexpression experiments. Availability and implementation KNIT is publicly available at http://knit.ims.bio. It is implemented with Django and Nuxtjs, with all major browsers supported. Supplementary information Supplementary data are available at Bioinformatics online.

中文翻译：

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KNIT 交互式基因网络

总结 KNIT 是一个 Web 应用程序，它提供了一个分层的有向图，说明一组基因如何连接到一个特定的感兴趣基因。它的主要目的是帮助研究人员辨别一个基因可能对其他基因和分子通路的表达产生的直接影响和间接影响，这是组学分析中一个非常常见的问题。因此，KNIT 为可能改变基因或蛋白质表达的实验（例如基因敲除和过表达实验）提供了深入的上下文信息。可用性和实施​​ KNIT 可在 http://knit.ims.bio 上公开获得。它使用 Django 和 Nuxtjs 实现，支持所有主流浏览器。补充信息 补充数据可在 Bioinformatics 在线获取。